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HomoloGene:31075. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   HMOX1,  H.sapiens
heme oxygenase (decycling) 1
    NP_002124.1
288 aa
   HMOX1,  P.troglodytes
heme oxygenase (decycling) 1
    XP_525579.2
288 aa
   HMOX1,  M.mulatta
heme oxygenase (decycling) 1
    XP_001113241.2
288 aa
   HMOX1,  C.lupus
heme oxygenase (decycling) 1
    NP_001181898.1
288 aa
   HMOX1,  B.taurus
heme oxygenase (decycling) 1
    NP_001014912.1
289 aa
   Hmox1,  M.musculus
heme oxygenase (decycling) 1
    NP_034572.1
289 aa
   Hmox1,  R.norvegicus
heme oxygenase (decycling) 1
    NP_036712.1
289 aa
   HMOX1,  G.gallus
heme oxygenase (decycling) 1
    NP_990675.1
296 aa
   hmox1,  X.tropicalis
heme oxygenase (decycling) 1
    XP_002934766.1
288 aa
   hmox1a,  D.rerio
heme oxygenase (decycling) 1a
    NP_001120988.1
272 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Heme oxygenase-1 deficiency.



Publications
Articles associated with genes and sequences of this homology group.

The cytoprotective enzyme heme oxygenase-1 suppresses Ebola virus replication.
Hill-Batorski L, et al. J Virol 87, 13795-802 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HemeO (cl17299)
  Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hmox1 includes H.sapiens HMOX1 and R.norvegicus Hmox1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 13 species)
Actinopterygii - bony fishes (13 transcripts, 9 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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