Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:37110. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   LRRTM3,  H.sapiens
leucine rich repeat transmembrane neuronal 3
    NP_821079.3
581 aa
   LRRTM3,  P.troglodytes
leucine rich repeat transmembrane neuronal 3
    XP_003312627.1
581 aa
   LRRTM3,  M.mulatta
leucine rich repeat transmembrane neuronal 3
    XP_002805754.1
581 aa
   LRRTM3,  C.lupus
leucine rich repeat transmembrane neuronal 3
    XP_546127.2
581 aa
   LRRTM3,  B.taurus
leucine rich repeat transmembrane neuronal 3
    NP_001096753.1
536 aa
   Lrrtm3,  M.musculus
leucine rich repeat transmembrane neuronal 3
    NP_848793.1
582 aa
   Lrrtm3,  R.norvegicus
leucine rich repeat transmembrane neuronal 3
    NP_001099857.1
582 aa
   LRRTM3,  G.gallus
leucine rich repeat transmembrane neuronal 3
    NP_001186474.1
581 aa
   lrrtm3,  X.tropicalis
leucine rich repeat transmembrane neuronal 3
    XP_002936907.2
514 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Effect of genetic variation in LRRTM3 on risk of Alzheimer disease.
Reitz C, et al. Arch Neurol 69, 894-900 (2012).
LRRTM3 is dispensable for amyloid-β production in mice.
Laakso T, et al. J Alzheimers Dis 31, 759-64 (2012).
Alpha T-catenin (CTNNA3): a gene in the hand is worth two in the nest.
Smith JD, et al. Cell Mol Life Sci 68, 2493-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR_8 (pfam13855)
  Leucine rich repeat.
LRRNT (cl02423)
  Leucine rich repeat N-terminal domain.
LRR_8 (pfam13855)
  Leucine rich repeat.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lrrtm3 includes H.sapiens LRRTM3 and R.norvegicus Lrrtm3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Aves - birds (2 transcripts, 2 species)

 

 

 

Write to the Help Desk