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HomoloGene:38187. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   KHK,  H.sapiens
ketohexokinase (fructokinase)
    NP_000212.1
298 aa
   KHK,  P.troglodytes
ketohexokinase (fructokinase)
    XP_003949817.1
298 aa
   KHK,  M.mulatta
ketohexokinase (fructokinase)
    XP_001089839.1
303 aa
   KHK,  C.lupus
ketohexokinase (fructokinase)
    NP_001182084.1
300 aa
   KHK,  B.taurus
ketohexokinase (fructokinase)
    NP_001069819.1
343 aa
   Khk,  M.musculus
ketohexokinase
    NP_032465.2
298 aa
   Khk,  R.norvegicus
ketohexokinase
    NP_114061.1
298 aa
   khk,  X.tropicalis
ketohexokinase (fructokinase)
    XP_002943517.2
213 aa
   khk,  D.rerio
ketohexokinase
    NP_001002636.1
299 aa
   AgaP_AGAP002483,  A.gambiae
AgaP_AGAP002483
    XP_563692.3
316 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Fructosuria.



Publications
Articles associated with genes and sequences of this homology group.

Structures of alternatively spliced isoforms of human ketohexokinase.
Trinh CH, et al. Acta Crystallogr D Biol Crystallogr 65, 201-11 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ribokinase_pfkB_like (cl00192)
  ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Khk includes H.sapiens KHK and R.norvegicus Khk.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (9 transcripts, 8 species)
Aves - birds (2 transcripts, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (4 transcripts, 4 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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