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HomoloGene:20191. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CHRM3,  H.sapiens
cholinergic receptor, muscarinic 3
    NP_000731.1
590 aa
   CHRM3,  P.troglodytes
cholinergic receptor, muscarinic 3
    NP_001129093.1
590 aa
   CHRM3,  M.mulatta
cholinergic receptor, muscarinic 3
    XP_001096287.1
590 aa
   CHRM3,  C.lupus
cholinergic receptor, muscarinic 3
    XP_546069.4
601 aa
   CHRM3,  B.taurus
cholinergic receptor, muscarinic 3
    NP_776695.1
590 aa
   Chrm3,  M.musculus
cholinergic receptor, muscarinic 3, cardiac
    NP_150372.1
589 aa
   Chrm3,  R.norvegicus
cholinergic receptor, muscarinic 3
    NP_036659.2
589 aa
   CHRM3,  G.gallus
cholinergic receptor, muscarinic 3
    NP_990730.1
639 aa
   LOC100493547,  X.tropicalis
muscarinic acetylcholine receptor M3-like
    XP_002935876.1
583 aa
   LOC101730815,  X.tropicalis
muscarinic acetylcholine receptor M3-like
    XP_004920895.1
395 aa
   chrm3a,  D.rerio
cholinergic receptor, muscarinic 3a
    XP_700381.4
595 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Muscarinic acetylcholine receptor 3 is dominant in myopia progression.
Lin HJ, et al. Invest Ophthalmol Vis Sci 53, 6519-25 (2012).
Critical metabolic roles of β-cell M3 muscarinic acetylcholine receptors.
Ruiz de Azua I, et al. Life Sci 91, 986-91 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Chrm3 includes H.sapiens CHRM3 and R.norvegicus Chrm3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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