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HomoloGene:20915. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CD81,  H.sapiens
CD81 molecule
    NP_004347.1
236 aa
   CD81,  P.troglodytes
CD81 molecule
    NP_001009023.1
236 aa
   CD81,  M.mulatta
CD81 molecule
    XP_001093228.1
236 aa
   LOC611606,  C.lupus
CD81 protein-like
    XP_005631797.1
305 aa
   CD81,  B.taurus
CD81 molecule
    NP_001030271.1
236 aa
   Cd81,  M.musculus
CD81 antigen
    NP_598416.1
236 aa
   Cd81,  R.norvegicus
Cd81 molecule
    NP_037219.1
236 aa
   CD81,  G.gallus
CD81 molecule
    NP_001025510.1
166 aa
   cd81,  X.tropicalis
CD81 protein
    NP_989271.1
237 aa
   zgc:92411,  D.rerio
zgc:92411
    NP_001003735.1
238 aa
   cd81,  D.rerio
CD81 antigen
    NP_571593.2
236 aa
   Tsp96F,  D.melanogaster
Tetraspanin 96F
    NP_524500.1
268 aa
   AgaP_AGAP000823,  A.gambiae
AgaP_AGAP000823
    XP_316787.2
268 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Immunodeficiency, common variable, 6.



Publications
Articles associated with genes and sequences of this homology group.

The association of CD81 polymorphisms with alloimmunization in sickle cell disease.
Tatari-Calderone Z, et al. Clin Dev Immunol 2013, 937846 (2013).
CD81 is a candidate tumor suppressor gene in human gastric cancer.
Yoo TH, et al. Cell Oncol (Dordr) 36, 141-53 (2013).
Hepatoma polarization limits CD81 and hepatitis C virus dynamics.
Harris HJ, et al. Cell Microbiol 15, 430-45 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tetraspannin (pfam00335)
  Tetraspanin family.
tetraspanin_LEL (cl02781)
  Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cd81 includes H.sapiens CD81 and R.norvegicus Cd81.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (14 transcripts, 9 species)
Mammalia - mammals (13 transcripts, 13 species)
Hyperoartia - vertebrates (3 transcripts, 1 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 8 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)

 

 

 

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