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HomoloGene:31297. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ATOH1,  H.sapiens
atonal homolog 1 (Drosophila)
    NP_005163.1
354 aa
   ATOH1,  P.troglodytes
atonal homolog 1 (Drosophila)
    NP_001012434.1
356 aa
   ATOH1,  M.mulatta
atonal homolog 1 (Drosophila)
    XP_001102247.1
354 aa
   ATOH1,  C.lupus
atonal homolog 1 (Drosophila)
    XP_544986.2
356 aa
   ATOH1,  B.taurus
atonal homolog 1 (Drosophila)
    NP_001091568.1
352 aa
   Atoh1,  M.musculus
atonal homolog 1 (Drosophila)
    NP_031526.1
351 aa
   Atoh1,  R.norvegicus
atonal homolog 1 (Drosophila)
    NP_001102708.1
351 aa
   ATOH1,  G.gallus
atonal homolog 1 (Drosophila)
    XP_004941187.1
126 aa
   atoh1,  X.tropicalis
atonal homolog 1 (Drosophila)
    XP_004911142.1
260 aa
   atoh1a,  D.rerio
atonal homolog 1a
    NP_571166.1
266 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The genetics of hair cell development and regeneration.
Groves AK, et al. Annu Rev Neurosci 36, 361-81 (2013).
Rodents rely on Merkel cells for texture discrimination tasks.
Maricich SM, et al. J Neurosci 32, 3296-300 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HLH (cl00081)
  Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atoh1 includes H.sapiens ATOH1 and R.norvegicus Atoh1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Actinopterygii - bony fishes (3 transcripts, 1 species)

 

 

 

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