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HomoloGene:3772. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FGB,  H.sapiens
fibrinogen beta chain
    NP_005132.2
491 aa
   FGB,  P.troglodytes
fibrinogen beta chain
    XP_517495.1
491 aa
   FGB,  M.mulatta
fibrinogen beta chain
    XP_001091998.1
491 aa
   FGB,  C.lupus
fibrinogen beta chain
    XP_005629424.1
495 aa
   FGB,  B.taurus
fibrinogen beta chain
    NP_001136389.1
495 aa
   Fgb,  M.musculus
fibrinogen beta chain
    NP_862897.1
481 aa
   Fgb,  R.norvegicus
fibrinogen beta chain
    NP_064456.2
479 aa
   FGB,  G.gallus
fibrinogen beta chain
    NP_001161155.1
480 aa
   fgb,  X.tropicalis
fibrinogen beta chain
    NP_001107962.1
490 aa
   fgb,  D.rerio
fibrinogen, B beta polypeptide
    NP_997939.1
485 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Dysfibrinogenemia, beta type.
Thrombophilia, dysfibrinogenemic.
Afibrinogenemia, congenital.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Fib_alpha (pfam08702)
  Fibrinogen alpha/beta chain family.
FReD (cl00085)
  Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fgb includes H.sapiens FGB and R.norvegicus Fgb.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (20 transcripts, 14 species)
Actinopterygii - bony fishes (12 transcripts, 11 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

 

 

 

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