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HomoloGene:3040. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FLT3,  H.sapiens
fms-related tyrosine kinase 3
    NP_004110.2
993 aa
   FLT3,  P.troglodytes
fms-related tyrosine kinase 3
    XP_509601.2
993 aa
   FLT3,  M.mulatta
fms-related tyrosine kinase 3
    XP_001117913.1
993 aa
   FLT3,  C.lupus
fms-related tyrosine kinase 3
    NP_001018647.1
993 aa
   FLT3,  B.taurus
fms-related tyrosine kinase 3
    XP_002691902.2
1035 aa
   Flt3,  M.musculus
FMS-like tyrosine kinase 3
    NP_034359.2
1000 aa
   Flt3,  R.norvegicus
fms-related tyrosine kinase 3
    NP_001094292.1
1000 aa
   FLT3,  G.gallus
fms-related tyrosine kinase 3
    XP_003640660.2
1006 aa
   flt3,  X.tropicalis
fms-related tyrosine kinase 3
    XP_004912442.1
916 aa
   flt3,  D.rerio
fms-related tyrosine kinase 3
    XP_001921760.2
956 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Leukemia, acute lymphoblastic.
Leukemia, acute myeloid, reduced survival in.
Leukemia, acute myeloid.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IGc2 (smart00408)
  Immunoglobulin C-2 Type.
ig (pfam00047)
  Immunoglobulin domain.
Pkinase_Tyr (pfam07714)
  Protein tyrosine kinase.
Ig (cl11960)
  Immunoglobulin domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Flt3 includes H.sapiens FLT3 and R.norvegicus Flt3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 10 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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