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HomoloGene:7623. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   AICDA,  H.sapiens
activation-induced cytidine deaminase
    NP_065712.1
198 aa
   AICDA,  P.troglodytes
activation-induced cytidine deaminase
    NP_001065277.1
198 aa
   LOC716378,  M.mulatta
activation-induced cytidine deaminase-like
    XP_001113641.1
198 aa
   AICDA,  C.lupus
activation-induced cytidine deaminase
    NP_001003380.1
198 aa
   AICDA,  B.taurus
activation-induced cytidine deaminase
    NP_001033771.1
199 aa
   Aicda,  M.musculus
activation-induced cytidine deaminase
    NP_033775.1
198 aa
   aicda,  R.norvegicus
activation-induced cytidine deaminase
    NP_001094249.1
198 aa
   AICDA,  G.gallus
activation-induced cytidine deaminase
    NP_001230151.1
198 aa
   LOC100497606,  X.tropicalis
activation-induced cytidine deaminase-like
    XP_002941248.1
201 aa
   aicda,  D.rerio
activation-induced cytidine deaminase
    NP_001008403.1
210 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Immunodeficiency with hyper-IgM, type 2.



Publications
Articles associated with genes and sequences of this homology group.

Differential programming of B cells in AID deficient mice.
Hogenbirk MA, et al. PLoS One 8, e69815 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
APOBEC_C (pfam05240)
  APOBEC-like C-terminal domain.
cytidine_deaminase-like (cl00269)
  Cytidine and deoxycytidylate deaminase zinc-binding region. The family contains cytidine deaminases, nucleoside deaminases, deoxycytidylate deaminases and riboflavin deaminases. Also included are the apoBec family of mRNA editing enzymes. All members ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Aicda includes H.sapiens AICDA and R.norvegicus aicda.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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