Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:374. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   NCF2,  H.sapiens
neutrophil cytosolic factor 2
    NP_000424.2
526 aa
   NCF2,  P.troglodytes
neutrophil cytosolic factor 2
    XP_001163353.1
526 aa
   NCF2,  C.lupus
neutrophil cytosolic factor 2
    NP_001095302.1
528 aa
   NCF2,  B.taurus
neutrophil cytosolic factor 2
    NP_776545.1
527 aa
   Ncf2,  M.musculus
neutrophil cytosolic factor 2
    NP_035007.1
525 aa
   Ncf2,  R.norvegicus
neutrophil cytosolic factor 2
    NP_001094454.1
527 aa
   NCF2,  G.gallus
neutrophil cytosolic factor 2
    XP_422288.2
520 aa
   ncf2,  X.tropicalis
neutrophil cytosolic factor 2
    NP_001029119.1
523 aa
   ncf2,  D.rerio
neutrophil cytosolic factor 2
    NP_001103932.1
500 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Chronic granulomatous disease due to deficiency of NCF-2.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TPR (cd00189)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
PB1 (cl02720)
  The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
PB1 (cl02720)
  The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
SH3 (cl17036)
  Src Homology 3 domain superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ncf2 includes H.sapiens NCF2 and R.norvegicus Ncf2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 12 species)
Actinopterygii - bony fishes (7 transcripts, 7 species)
Amniota - vertebrates (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

 

 

 

Write to the Help Desk