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HomoloGene:28. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   AR,  H.sapiens
androgen receptor
    NP_000035.2
920 aa
   AR,  M.mulatta
androgen receptor
    NP_001028083.1
895 aa
   AR,  C.lupus
androgen receptor
    NP_001003053.1
907 aa
   AR,  B.taurus
androgen receptor
    NP_001231056.1
890 aa
   Ar,  M.musculus
androgen receptor
    NP_038504.1
899 aa
   Ar,  R.norvegicus
androgen receptor
    NP_036634.1
902 aa
   AR,  G.gallus
androgen receptor
    NP_001035179.1
703 aa
   ar,  X.tropicalis
androgen receptor
    XP_002941888.2
788 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Prostate cancer, susceptibility to.
Androgen insensitivity.
Hypospadias, perineal.
Spinal and bulbar muscular atrophy of Kennedy.
Breast cancer, male, with Reifenstein syndrome.
Prostate cancer.



Publications
Articles associated with genes and sequences of this homology group.

Visualising androgen receptor activity in male and female mice.
Dart DA, et al. PLoS One 8, e71694 (2013).
Androgen receptors in early and castration resistant prostate cancer: friend or foe?
Pelekanou V, et al. Hormones (Athens) 12, 224-35 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Androgen_recep (pfam02166)
  Androgen receptor.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ar includes H.sapiens AR and R.norvegicus Ar.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 15 species)
Actinopterygii - bony fishes (14 transcripts, 8 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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