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HomoloGene:68174. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CHD1,  H.sapiens
chromodomain helicase DNA binding protein 1
    NP_001261.2
1710 aa
   CHD1,  P.troglodytes
chromodomain helicase DNA binding protein 1
    XP_517850.2
1710 aa
   CHD1,  M.mulatta
chromodomain helicase DNA binding protein 1
    XP_001097125.1
1712 aa
   CHD1,  C.lupus
chromodomain helicase DNA binding protein 1
    XP_848459.1
1711 aa
   CHD1,  B.taurus
chromodomain helicase DNA binding protein 1
    NP_001178977.1
1810 aa
   Chd1,  M.musculus
chromodomain helicase DNA binding protein 1
    NP_031716.2
1711 aa
   Chd1,  R.norvegicus
chromodomain helicase DNA binding protein 1
    NP_001100935.1
1711 aa
   CHD1,  G.gallus
chromodomain helicase DNA binding protein 1
    NP_990272.1
1808 aa
   zgc:173506,  D.rerio
zgc:173506
    NP_001121770.2
1693 aa
   CHD1,  S.cerevisiae
CHD1
    NP_011091.1
1468 aa
   KLLA0C17578g,  K.lactis
KLLA0C17578g
    XP_452985.1
1525 aa
   AGOS_AGR123C,  E.gossypii
AGOS_AGR123C
    NP_986789.1
1422 aa
   hrp3,  S.pombe
hrp3
    NP_594967.1
1388 aa
   hrp1,  S.pombe
hrp1
    NP_593660.1
1373 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

A DNA test to sex most birds.
Griffiths R, et al. Mol Ecol 7, 1071-5 (1998).
A CHD1 gene is Z chromosome linked in the chicken Gallus domesticus.
Griffiths R & Korn RM. Gene 197, 225-9 (1997).
DNA-binding and chromatin localization properties of CHD1.
Stokes DG & Perry RP. Mol Cell Biol 15, 2745-53 (1995).
Structural polymorphism of chromodomains in Chd1.
Okuda M, et al. J Mol Biol 365, 1047-62 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PHA03420 (PHA03420)
  E4 protein; Provisional.
DUF4208 (pfam13907)
  Domain of unknown function (DUF4208).
SANT_TRF (cd11660)
  Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family.
SANT (cl15779)
  'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
SNF2_N (pfam00176)
  SNF2 family N-terminal domain.
HELICc (cd00079)
  Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
SNF2_N (pfam00176)
  SNF2 family N-terminal domain.
DUF1777 (pfam08648)
  Protein of unknown function (DUF1777).
CHROMO (cl17459)
  Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence implicates the chromo domain in the binding activity of these proteins to methylated histone tails and maybe RNA. May occur as single instance, in a tandem arrangement or followd by a related "chromo shadow" domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Chd1 includes H.sapiens CHD1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 11 species)
Actinopterygii - bony fishes (12 transcripts, 7 species)
Aves - birds (5 transcripts, 2 species)
Amphibia - amphibians (4 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (2 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

 

 

 

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