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HomoloGene:20544. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MMP1,  H.sapiens
matrix metallopeptidase 1 (interstitial collagenase)
    NP_002412.1
469 aa
   MMP1,  P.troglodytes
matrix metallopeptidase 1 (interstitial collagenase)
    XP_508722.2
469 aa
   MMP1,  M.mulatta
matrix metallopeptidase 1 (interstitial collagenase)
    XP_001098302.1
469 aa
   LOC489428,  C.lupus
interstitial collagenase-like
    XP_546546.3
468 aa
   LOC100848085,  B.taurus
interstitial collagenase-like
    XP_003586977.1
469 aa
   MMP1,  B.taurus
matrix metallopeptidase 1 (interstitial collagenase)
    NP_776537.1
469 aa
   Mmp1a,  M.musculus
matrix metallopeptidase 1a (interstitial collagenase)
    NP_114395.1
464 aa
   Mmp1,  R.norvegicus
matrix metallopeptidase 1 (interstitial collagenase)
    NP_001128002.1
464 aa
   MMP1,  G.gallus
matrix metallopeptidase 1 (interstitial collagenase)
    XP_417176.1
466 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
COPD, rate of decline of lung function in.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PG_binding_1 (pfam01471)
  Putative peptidoglycan binding domain.
HX (cd00094)
  Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
PG_binding_1 (pfam01471)
  Putative peptidoglycan binding domain.
ZnMc (cl00064)
  Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mmp1a includes H.sapiens MMP1 and R.norvegicus Mmp1a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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