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HomoloGene:1420. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   HAPLN1,  H.sapiens
hyaluronan and proteoglycan link protein 1
    NP_001875.1
354 aa
   HAPLN1,  P.troglodytes
hyaluronan and proteoglycan link protein 1
    XP_001147083.1
354 aa
   HAPLN1,  M.mulatta
hyaluronan and proteoglycan link protein 1
    XP_001112341.1
354 aa
   HAPLN1,  C.lupus
hyaluronan and proteoglycan link protein 1
    XP_849484.1
354 aa
   HAPLN1,  B.taurus
hyaluronan and proteoglycan link protein 1
    NP_776713.1
354 aa
   Hapln1,  M.musculus
hyaluronan and proteoglycan link protein 1
    NP_038528.3
356 aa
   Hapln1,  R.norvegicus
hyaluronan and proteoglycan link protein 1
    NP_062062.2
354 aa
   HAPLN1,  G.gallus
hyaluronan and proteoglycan link protein 1
    NP_990813.1
355 aa
   hapln1,  X.tropicalis
hyaluronan and proteoglycan link protein 1
    XP_002933976.2
350 aa
   hapln1b,  D.rerio
hyaluronan and proteoglycan link protein 1b
    XP_002663704.3
353 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Production of cartilage link protein by human granulosa-lutein cells.
Sun GW, et al. J Endocrinol 175, 505-15 (2002).
Fibrocartilage in the transverse ligament of the human atlas.
Milz S, et al. Spine (Phila Pa 1976) 26, 1765-71 (2001).
Glycation induced crosslinking of link proteins, in vivo and in vitro.
Pokharna HK & Pottenger LA. J Surg Res 94, 35-42 (2000).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Link_Domain (cl02612)
  The link domain is a hyaluronan (HA)-binding domain. It functions to mediate adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It is found in the CD44 receptor and in human TSG-6. TSG-6 is the protein product of the tumor ...
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hapln1 includes H.sapiens HAPLN1 and R.norvegicus Hapln1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (14 transcripts, 8 species)
Mammalia - mammals (11 transcripts, 10 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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