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HomoloGene:5017. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   COX2,  H.sapiens
COX2
    YP_003024029.1
227 aa
   COX2,  P.troglodytes
COX2
    NP_008189.1
227 aa
   COX2,  C.lupus
COX2
    NP_008474.4
227 aa
   COX2,  B.taurus
COX2
    YP_209208.1
227 aa
   COX2,  M.musculus
COX2
    NP_904331.1
227 aa
   COX2,  R.norvegicus
COXII
    YP_665632.1
227 aa
   COX2,  G.gallus
COX2
    NP_006918.1
227 aa
   COX2,  X.tropicalis
COX2
    YP_203373.1
229 aa
   COX2,  D.rerio
COX2
    NP_059334.1
230 aa
   COX2,  D.melanogaster
COX2
    NP_008279.1
228 aa
   COX2,  A.gambiae
COX2
    NP_008071.1
228 aa
   COX2,  C.elegans
COX2
    NP_006962.1
231 aa
   COX2,  S.cerevisiae
COX2
    NP_009326.1
251 aa
   COX2,  K.lactis
COX2
    YP_054502.1
256 aa
   AGOS_AMI001W,  E.gossypii
AGOS_AMI001W
    NP_987078.1
248 aa
   cox2,  S.pombe
cox2
    NP_039508.1
248 aa
   cox2,  A.thaliana
cox2
    NP_085487.1
260 aa
   cox2,  O.sativa
cox2
    YP_002000571.1
260 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

A study on expression pattern of cyclooxygenase-2 in carcinoma of cervix.
Bandyopadhyay R, et al. Indian J Pathol Microbiol 54, 695-9 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
COX2 (MTH00080)
  cytochrome c oxidase subunit II; Provisional.
COX2 (pfam00116)
  Cytochrome C oxidase subunit II, periplasmic domain.
COX2_TM (pfam02790)
  Cytochrome C oxidase subunit II, transmembrane domain.
COX2 (MTH00154)
  cytochrome c oxidase subunit II; Provisional.
Cupredoxin (cl19115)
  Cupredoxin superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus mt-Co2 includes H.sapiens COX2 and R.norvegicus COX2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (36 transcripts, 15 species)
Actinopterygii - bony fishes (14 transcripts, 11 species)
Ascidiacea - tunicates (6 transcripts, 3 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (3 transcripts, 3 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (24 transcripts, 13 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (5 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (4 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (28 transcripts, 19 species)
Liliopsida - monocots (8 transcripts, 6 species)
Coniferopsida - conifers (4 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (2 transcripts, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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