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HomoloGene:2478. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TRPC1,  H.sapiens
transient receptor potential cation channel, subfamily C, member 1
    NP_001238774.1
793 aa
   TRPC1,  P.troglodytes
transient receptor potential cation channel, subfamily C, member 1
    XP_003950257.1
793 aa
   TRPC1,  M.mulatta
transient receptor potential cation channel, subfamily C, member 1
    XP_001112011.2
758 aa
   TRPC1,  C.lupus
transient receptor potential cation channel, subfamily C, member 1
    XP_003639879.1
794 aa
   TRPC1,  B.taurus
transient receptor potential cation channel, subfamily C, member 1
    NP_776901.1
793 aa
   Trpc1,  M.musculus
transient receptor potential cation channel, subfamily C, member 1
    NP_035773.1
809 aa
   Trpc1,  R.norvegicus
transient receptor potential cation channel, subfamily C, member 1
    NP_446010.1
759 aa
   TRPC1,  G.gallus
transient receptor potential cation channel, subfamily C, member 1
    NP_001004409.1
781 aa
   trpc1,  X.tropicalis
transient receptor potential cation channel, subfamily C, member 1
    XP_002937145.2
896 aa
   trpc1,  D.rerio
transient receptor potential cation channel, subfamily C, member 1
    NP_001185590.1
796 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension.
Malczyk M, et al. Am J Respir Crit Care Med 188, 1451-9 (2013).
On the role of TRPC1 in control of Ca2+ influx, cell volume, and cell cycle.
Madsen CP, et al. Am J Physiol Cell Physiol 303, C625-34 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TRP_2 (pfam08344)
  Transient receptor ion channel II.
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
TRP_2 (pfam08344)
  Transient receptor ion channel II.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Trpc1 includes H.sapiens TRPC1 and R.norvegicus Trpc1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (11 transcripts, 9 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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