Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:10771. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FGF23,  H.sapiens
fibroblast growth factor 23
    NP_065689.1
251 aa
   FGF23,  P.troglodytes
fibroblast growth factor 23
    XP_001157070.1
251 aa
   FGF23,  M.mulatta
fibroblast growth factor 23
    XP_001099705.1
251 aa
   FGF23,  C.lupus
fibroblast growth factor 23
    XP_854580.1
312 aa
   FGF23,  B.taurus
fibroblast growth factor 23
    XP_002687926.1
245 aa
   Fgf23,  M.musculus
fibroblast growth factor 23
    NP_073148.1
251 aa
   Fgf23,  R.norvegicus
fibroblast growth factor 23
    NP_570110.1
251 aa
   FGF23,  G.gallus
fibroblast growth factor 23
    XP_425663.1
254 aa
   fgf23.1,  X.tropicalis
fibroblast growth factor 23, gene 1
    XP_002940347.2
244 aa
   LOC100496800,  X.tropicalis
fibroblast growth factor 23-like
    XP_002940351.1
254 aa
   fgf23,  D.rerio
fibroblast growth factor 23
    NP_001009564.2
258 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hypophosphatemic rickets, autosomal dominant.
Tumoral calcinosis, hyperphosphatemic, familial.
calcinosis, tumoral, with hyperphosphatemia.
Osteomalacia, tumor-induced.



Publications
Articles associated with genes and sequences of this homology group.

The value of serum FGF-23 as a cardiovascular marker in HD patients.
Sany D, et al. Saudi J Kidney Dis Transpl 25, 44-52 (2014).
Calcium regulates FGF-23 expression in bone.
David V, et al. Endocrinology 154, 4469-82 (2013).
The changing face of hypophosphatemic disorders in the FGF-23 era.
Lee JY & Imel EA. Pediatr Endocrinol Rev 10 Suppl 2, 367-79 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FGF (cl00060)
  Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fgf23 includes H.sapiens FGF23 and R.norvegicus Fgf23.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (4 transcripts, 4 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

Write to the Help Desk