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HomoloGene:40729. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ELAVL4,  H.sapiens
ELAV like neuron-specific RNA binding protein 4
    NP_068771.2
380 aa
   ELAVL4,  P.troglodytes
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4
    XP_001135779.1
371 aa
   ELAVL4,  M.mulatta
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4
    XP_001110750.1
371 aa
   ELAVL4,  C.lupus
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4
    XP_005629074.1
385 aa
   ELAVL4,  B.taurus
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
    NP_001075075.1
366 aa
   Elavl4,  M.musculus
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
    NP_001156871.1
371 aa
   Elavl4,  R.norvegicus
ELAV like neuron-specific RNA binding protein 4
    NP_001071119.1
373 aa
   ELAVL4,  G.gallus
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
    NP_990161.1
371 aa
   elavl4,  X.tropicalis
ELAV like neuron-specific RNA binding protein 4
    NP_001096525.1
400 aa
   elavl4,  D.rerio
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
    NP_001231529.1
411 aa
   Rbp9,  D.melanogaster
RNA-binding protein 9
    NP_001259974.1
684 aa
   exc-7,  C.elegans
exc-7
    NP_496057.1
456 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Neuropathy, paraneoplastic sensory.



Publications
Articles associated with genes and sequences of this homology group.

Reduced expression of ELAVL4 in male meningioma patients.
Stawski R, et al. Brain Tumor Pathol 30, 160-6 (2013).
Tolerance to the neuron-specific paraneoplastic HuD antigen.
DeLuca I, et al. PLoS One 4, e5739 (2009).
Molecular analysis of the HuD gene in neuroendocrine lung cancers.
D'Alessandro V, et al. Lung Cancer 67, 69-75 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RRM_SF (cl17169)
  RNA recognition motif (RRM) superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Elavl4 includes H.sapiens ELAVL4 and R.norvegicus Elavl4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 12 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 7 species)
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (3 transcripts, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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