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HomoloGene:20920. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CRHR1,  H.sapiens
corticotropin releasing hormone receptor 1
    NP_001138618.1
444 aa
   CRHR1,  P.troglodytes
corticotropin releasing hormone receptor 1
    XP_003953028.1
447 aa
   CRHR1,  M.mulatta
corticotropin releasing hormone receptor 1
    NP_001027975.1
415 aa
   CRHR1,  C.lupus
corticotropin releasing hormone receptor 1
    XP_005624253.1
416 aa
   CRHR1,  B.taurus
corticotropin releasing hormone receptor 1
    NP_776712.1
415 aa
   Crhr1,  M.musculus
corticotropin releasing hormone receptor 1
    NP_031788.1
415 aa
   Crhr1,  R.norvegicus
corticotropin releasing hormone receptor 1
    NP_112261.1
415 aa
   CRHR1,  G.gallus
corticotropin releasing hormone receptor 1
    NP_989652.1
420 aa
   LOC100498637,  X.tropicalis
corticotropin-releasing factor receptor 1-like
    XP_002938039.2
415 aa
   crhr1,  D.rerio
corticotropin releasing hormone receptor 1
    XP_696346.3
430 aa
   Dh44-R2,  D.melanogaster
Diuretic hormone 44 receptor 2
    NP_725175.3
475 aa
   GPRDIH1,  A.gambiae
GPRDIH1
    XP_315466.4
538 aa
   C18B12.2,  C.elegans
C18B12.2
    NP_510496.1
454 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Structure of class B GPCR corticotropin-releasing factor receptor 1.
Hollenstein K, et al. Nature 499, 438-43 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HRM (pfam02793)
  Hormone receptor domain.
7tm_2 (pfam00002)
  7 transmembrane receptor (Secretin family).
HRM (cl02422)
  Hormone receptor domain.
7tm_2 (cl19289)
  7 transmembrane receptor (Secretin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Crhr1 includes H.sapiens CRHR1 and R.norvegicus Crhr1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 7 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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