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HomoloGene:55444. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ITGB3,  H.sapiens
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
    NP_000203.2
788 aa
   ITGB3,  P.troglodytes
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
    XP_523684.2
788 aa
   ITGB3,  M.mulatta
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
    XP_001116013.1
788 aa
   ITGB3,  C.lupus
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
    NP_001003162.1
784 aa
   ITGB3,  B.taurus
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
    NP_001193419.1
784 aa
   Itgb3,  M.musculus
integrin beta 3
    NP_058060.2
787 aa
   Itgb3,  R.norvegicus
integrin, beta 3
    NP_714942.1
787 aa
   ITGB3,  G.gallus
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
    NP_989646.1
781 aa
   itgb3,  X.tropicalis
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
    XP_002942401.2
785 aa
   itgb3b,  D.rerio
integrin beta 3b
    NP_001076417.1
790 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Glanzmann thrombasthenia, type B.



Publications
Articles associated with genes and sequences of this homology group.

Platelet alloantigen polymorphism and migraine headaches.
Bhaskar S & Abdullah JM. Neurosciences (Riyadh) 18, 185-6 (2013).
[Platelet intregrin beta3 A1/A2 polymorphism in women with stillbirth].
Ivanov P, et al. Akush Ginekol (Sofiia) 51, 8-12 (2012).
Sca-1 is involved in the adhesion of myosphere cells to αVβ3 integrin.
Penvose A & Westerman KA. Biol Open 1, 839-47 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Integrin_b_cyt (pfam08725)
  Integrin beta cytoplasmic domain.
Integrin_beta (pfam00362)
  Integrin, beta chain.
Integrin_B_tail (pfam07965)
  Integrin beta tail domain.
Integrin_B_tail (pfam07965)
  Integrin beta tail domain.
Integrin_beta (cl17693)
  Integrin, beta chain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Itgb3 includes H.sapiens ITGB3 and R.norvegicus Itgb3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 11 species)
Actinopterygii - bony fishes (13 transcripts, 7 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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