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HomoloGene:55661. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NRAS,  H.sapiens
neuroblastoma RAS viral (v-ras) oncogene homolog
NP_002515.1
189 aa
NRAS,  P.troglodytes
neuroblastoma RAS viral (v-ras) oncogene homolog
XP_001149822.1
189 aa
NRAS,  C.lupus
neuroblastoma RAS viral (v-ras) oncogene homolog
XP_848629.1
189 aa
NRAS,  B.taurus
neuroblastoma RAS viral (v-ras) oncogene homolog
NP_001091458.1
189 aa
Nras,  M.musculus
neuroblastoma ras oncogene
NP_035067.2
189 aa
Nras,  R.norvegicus
neuroblastoma ras oncogene
NP_542944.1
189 aa
NRAS,  G.gallus
neuroblastoma RAS viral (v-ras) oncogene homolog
NP_001012567.1
189 aa
LOC549517,  X.tropicalis
uncharacterized LOC549517
NP_001016763.1
189 aa
nras,  D.rerio
neuroblastoma RAS viral (v-ras) oncogene homolog
NP_571220.1
188 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Colorectal cancer.
Thyroid carcinoma, follicular.



Publications
Articles associated with genes and sequences of this homology group.

Characteristics of lung cancers harboring NRAS mutations.
Ohashi K, et al. Clin Cancer Res 19, 2584-91 (2013).
Genetic alterations in RAS-regulated pathway in acral lentiginous melanoma.
Puig-Butillé JA, et al. Exp Dermatol 22, 148-50 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nras includes H.sapiens NRAS and R.norvegicus Nras.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 13 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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