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HomoloGene:1265. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ATF3,  H.sapiens
activating transcription factor 3
    NP_001665.1
181 aa
   ATF3,  P.troglodytes
activating transcription factor 3
    XP_524528.3
181 aa
   ATF3,  M.mulatta
activating transcription factor 3
    XP_001107925.1
181 aa
   ATF3,  C.lupus
activating transcription factor 3
    XP_852475.1
181 aa
   ATF3,  B.taurus
activating transcription factor 3
    NP_001039658.1
181 aa
   Atf3,  M.musculus
activating transcription factor 3
    NP_031524.2
181 aa
   Atf3,  R.norvegicus
activating transcription factor 3
    NP_037044.1
181 aa
   ATF3,  G.gallus
activating transcription factor 3
    XP_004935391.1
181 aa
   atf3,  X.tropicalis
activating transcription factor 3
    XP_002934744.1
181 aa
   atf3,  D.rerio
activating transcription factor 3
    NP_957258.1
202 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

ATF3 plays a role in adipocyte hypoxia-mediated mitochondria dysfunction in obesity.
Jang MK, et al. Biochem Biophys Res Commun 431, 421-7 (2013).
Activating transcription factor 3 and the nervous system.
Hunt D, et al. Front Mol Neurosci 5, 7 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
B_zip1 (cl02576)
  basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atf3 includes H.sapiens ATF3 and R.norvegicus Atf3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 10 species)
Actinopterygii - bony fishes (9 transcripts, 7 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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