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HomoloGene:22726. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GLS,  H.sapiens
glutaminase
    NP_055720.3
669 aa
   GLS,  P.troglodytes
glutaminase
    XP_001167502.1
669 aa
   GLS,  M.mulatta
glutaminase
    XP_002799041.1
609 aa
   GLS,  C.lupus
glutaminase
    XP_545570.2
679 aa
   GLS,  B.taurus
glutaminase
    NP_001071432.1
603 aa
   Gls,  M.musculus
glutaminase
    NP_001074550.1
674 aa
   Gls,  R.norvegicus
glutaminase
    NP_036701.2
674 aa
   GLS,  G.gallus
glutaminase
    NP_001026419.1
668 aa
   gls,  X.tropicalis
glutaminase
    XP_002931560.2
551 aa
   glsa,  D.rerio
glutaminase a
    NP_001038509.1
591 aa
   glsb,  D.rerio
glutaminase b
    XP_693171.3
635 aa
   CG42708,  D.melanogaster
CG42708
    NP_725217.1
737 aa
   glna-1,  C.elegans
glna-1
    NP_497055.2
793 aa
   glna-3,  C.elegans
glna-3
    NP_492162.1
583 aa
   glna-2,  C.elegans
glna-2
    NP_495675.1
605 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Glutaminase: a hot spot for regulation of cancer cell metabolism?
Erickson JW & Cerione RA. Oncotarget 1, 734-40 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ank_4 (pfam13637)
  Ankyrin repeats (many copies).
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
Ank_4 (pfam13637)
  Ankyrin repeats (many copies).
Glutaminase (cl00907)
  Glutaminase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gls includes H.sapiens GLS and R.norvegicus Gls.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (22 transcripts, 9 species)
Mammalia - mammals (14 transcripts, 11 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (5 transcripts, 5 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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