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HomoloGene:10859. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GBA2,  H.sapiens
glucosidase, beta (bile acid) 2
    NP_065995.1
927 aa
   GBA2,  P.troglodytes
glucosidase, beta (bile acid) 2
    XP_001167923.2
933 aa
   GBA2,  M.mulatta
glucosidase, beta (bile acid) 2
    XP_001084705.1
927 aa
   GBA2,  C.lupus
glucosidase, beta (bile acid) 2
    XP_005626843.1
917 aa
   GBA2,  B.taurus
glucosidase, beta (bile acid) 2
    XP_002689726.1
918 aa
   Gba2,  M.musculus
glucosidase beta 2
    NP_766280.2
918 aa
   Gba2,  R.norvegicus
glucosidase beta 2
    NP_001013109.2
904 aa
   GBA2,  G.gallus
glucosidase, beta (bile acid) 2
    XP_003642968.1
853 aa
   gba2,  X.tropicalis
glucosidase, beta (bile acid) 2
    XP_002943495.2
446 aa
   gba2,  D.rerio
glucosidase, beta (bile acid) 2
    XP_687652.2
851 aa
   CG33090,  D.melanogaster
CG33090
    NP_788055.2
948 aa
   AgaP_AGAP008830,  A.gambiae
AgaP_AGAP008830
    XP_319575.4
913 aa
   hpo-13,  C.elegans
hpo-13
    NP_001021680.1
959 aa
   R08F11.1,  C.elegans
R08F11.1
    NP_504047.2
830 aa
   AT3G24180,  A.thaliana
AT3G24180
    NP_189060.2
950 aa
   Os10g0473400,  O.sativa
Os10g0473400
    NP_001064833.1
974 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.

Molecular cloning and expression of human bile acid beta-glucosidase.
Matern H, et al. J Biol Chem 276, 37929-33 (2001).
β-Glucosidase 2 (GBA2) activity and imino sugar pharmacology.
Ridley CM, et al. J Biol Chem 288, 26052-66 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Bac_rhamnosid (cl01801)
  Bacterial alpha-L-rhamnosidase.
DUF608 (pfam04685)
  Protein of unknown function, DUF608.
GBA2_N (pfam12215)
  beta-Glucocerebrosidase 2 N terminal.
DUF608 (pfam04685)
  Protein of unknown function, DUF608.
GBA2_N (pfam12215)
  beta-Glucocerebrosidase 2 N terminal.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gba2 includes H.sapiens GBA2 and R.norvegicus Gba2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (39 transcripts, 23 species)
Liliopsida - monocots (20 transcripts, 9 species)
Coniferopsida - conifers (5 transcripts, 3 species)
Bryopsida - mosses (3 transcripts, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chordata
Mammalia - mammals (21 transcripts, 12 species)
Actinopterygii - bony fishes (9 transcripts, 9 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 8 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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