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HomoloGene:3795. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ATP6V0A1,  H.sapiens
ATPase, H+ transporting, lysosomal V0 subunit a1
    NP_001123493.1
837 aa
   ATP6V0A1,  P.troglodytes
ATPase, H+ transporting, lysosomal V0 subunit a1
    XP_001165034.1
837 aa
   ATP6V0A1,  M.mulatta
ATPase, H+ transporting, lysosomal V0 subunit a1
    XP_001095161.2
803 aa
   ATP6V0A1,  C.lupus
ATPase, H+ transporting, lysosomal V0 subunit a1
    XP_849622.2
838 aa
   ATP6V0A1,  B.taurus
ATPase, H+ transporting, lysosomal V0 subunit a1
    NP_777179.1
838 aa
   Atp6v0a1,  M.musculus
ATPase, H+ transporting, lysosomal V0 subunit A1
    NP_058616.1
838 aa
   Atp6v0a1,  R.norvegicus
ATPase, H+ transporting, lysosomal V0 subunit A1
    NP_113792.2
838 aa
   ATP6V0A1,  G.gallus
ATPase, H+ transporting, lysosomal V0 subunit a1
    NP_990055.1
838 aa
   atp6v0a1,  X.tropicalis
ATPase, H+ transporting, lysosomal V0 subunit a1
    NP_001090714.1
837 aa
   Vha100-1,  D.melanogaster
Vacuolar H[+] ATPase subunit 100-1
    NP_651672.1
855 aa
   AgaP_AGAP003711,  A.gambiae
AgaP_AGAP003711
    XP_003436582.1
855 aa
   unc-32,  C.elegans
unc-32
    NP_001023017.1
905 aa
   VPH1,  S.cerevisiae
VPH1
    NP_014913.3
840 aa
   KLLA0C07491g,  K.lactis
KLLA0C07491g
    XP_452533.1
829 aa
   AGOS_ADR177C,  E.gossypii
AGOS_ADR177C
    NP_984273.2
839 aa
   vph1,  S.pombe
vph1
    NP_594219.2
831 aa
   MGG_03947,  M.oryzae
MGG_03947
    XP_003719917.1
860 aa
   NCU03463,  N.crassa
NCU03463
    XP_956054.1
856 aa
   VHA-A1,  A.thaliana
VHA-A1
    NP_850122.1
817 aa
   Os01g0834200,  O.sativa
Os01g0834200
    NP_001044718.2
818 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

On the role of v-ATPase V0a1-dependent degradation in Alzheimer disease.
Williamson WR & Hiesinger PR. Commun Integr Biol 3, 604-7 (2010).
A new view of an old pore.
Bajjalieh S. Cell 121, 496-7 (2005).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
V_ATPase_I (pfam01496)
  V-type ATPase 116kDa subunit family.
V_ATPase_I (pfam01496)
  V-type ATPase 116kDa subunit family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atp6v0a1 includes H.sapiens ATP6V0A1 and R.norvegicus Atp6v0a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (21 transcripts, 15 species)
Actinopterygii - bony fishes (8 transcripts, 4 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Amphibia - amphibians (5 transcripts, 2 species)
Aves - birds (4 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (17 transcripts, 12 species)
Arachnida - arachnids (4 transcripts, 2 species)
Malacostraca - crustaceans (3 transcripts, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (6 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (5 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (2 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (4 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Annelida
Hirudinida - segmented worms (2 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (33 transcripts, 19 species)
Liliopsida - monocots (13 transcripts, 7 species)
Coniferopsida - conifers (3 transcripts, 1 species)
Bryopsida - mosses (2 transcripts, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (7 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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