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HomoloGene:15601. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ATRIP,  H.sapiens
ATR interacting protein
    NP_569055.1
791 aa
   ATRIP,  P.troglodytes
ATR interacting protein
    XP_001156485.2
791 aa
   ATRIP,  M.mulatta
ATR interacting protein
    XP_001112538.2
790 aa
   ATRIP,  C.lupus
ATR interacting protein
    XP_005632647.1
792 aa
   ATRIP,  B.taurus
ATR interacting protein
    NP_001096800.1
789 aa
   Atrip,  M.musculus
ATR interacting protein
    NP_766362.2
785 aa
   Atrip,  R.norvegicus
ATR interacting protein
    NP_001100329.1
784 aa
   ATRIP,  G.gallus
ATR interacting protein
    NP_001243080.1
822 aa
   atrip,  X.tropicalis
ATR interacting protein
    NP_001015895.2
736 aa
   atrip,  D.rerio
ATR interacting protein
    NP_001038332.1
737 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

ATR signalling: more than meeting at the fork.
Nam EA & Cortez D. Biochem J 436, 527-36 (2011).
Centrosomal localization of DNA damage checkpoint proteins.
Zhang S, et al. J Cell Biochem 101, 451-65 (2007).
ATRIP associates with replication protein A-coated ssDNA through multiple interactions.
Namiki Y & Zou L. Proc Natl Acad Sci U S A 103, 580-5 (2006).
ATRIP oligomerization is required for ATR-dependent checkpoint signaling.
Ball HL & Cortez D. J Biol Chem 280, 31390-6 (2005).
Function of a conserved checkpoint recruitment domain in ATRIP proteins.
Ball HL, et al. Mol Cell Biol 27, 3367-77 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HCR (pfam07111)
  Alpha helical coiled-coil rod protein (HCR).
Prefoldin_2 (pfam01920)
  Prefoldin subunit.
Tropomyosin_1 (pfam12718)
  Tropomyosin like.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atrip includes H.sapiens ATRIP and R.norvegicus Atrip.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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