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HomoloGene:15601. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   ATRIP,  H.sapiens
ATR interacting protein
791 aa
   ATRIP,  P.troglodytes
ATR interacting protein
791 aa
   ATRIP,  M.mulatta
ATR interacting protein
790 aa
   ATRIP,  C.lupus
ATR interacting protein
792 aa
   ATRIP,  B.taurus
ATR interacting protein
789 aa
   Atrip,  M.musculus
ATR interacting protein
785 aa
   Atrip,  R.norvegicus
ATR interacting protein
784 aa
   ATRIP,  G.gallus
ATR interacting protein
822 aa
   atrip,  X.tropicalis
ATR interacting protein
736 aa
   atrip,  D.rerio
ATR interacting protein
737 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

ATR signalling: more than meeting at the fork.
Nam EA & Cortez D. Biochem J 436, 527-36 (2011).
Centrosomal localization of DNA damage checkpoint proteins.
Zhang S, et al. J Cell Biochem 101, 451-65 (2007).
ATRIP associates with replication protein A-coated ssDNA through multiple interactions.
Namiki Y & Zou L. Proc Natl Acad Sci U S A 103, 580-5 (2006).
ATRIP oligomerization is required for ATR-dependent checkpoint signaling.
Ball HL & Cortez D. J Biol Chem 280, 31390-6 (2005).
Function of a conserved checkpoint recruitment domain in ATRIP proteins.
Ball HL, et al. Mol Cell Biol 27, 3367-77 (2007).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HCR (pfam07111)
  Alpha helical coiled-coil rod protein (HCR).
Prefoldin_2 (pfam01920)
  Prefoldin subunit.
Tropomyosin_1 (pfam12718)
  Tropomyosin like.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atrip includes H.sapiens ATRIP and R.norvegicus Atrip.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)




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