Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:147. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GSN,  H.sapiens
gelsolin
    NP_000168.1
782 aa
   GSN,  P.troglodytes
gelsolin
    XP_001161890.1
782 aa
   GSN,  M.mulatta
gelsolin
    XP_001093567.1
784 aa
   GSN,  C.lupus
gelsolin
    XP_005627064.1
865 aa
   GSN,  B.taurus
gelsolin
    NP_001106755.1
781 aa
   Gsn,  M.musculus
gelsolin
    NP_666232.2
780 aa
   Gsn,  R.norvegicus
gelsolin
    NP_001004080.1
780 aa
   GSN,  G.gallus
gelsolin
    NP_990265.1
778 aa
   gsn,  X.tropicalis
gelsolin
    NP_001016856.1
728 aa
   gsna,  D.rerio
gelsolin a
    NP_001012312.1
730 aa
   MGG_10059,  M.oryzae
MGG_10059
    XP_003717447.1
426 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Amyloidosis, Finnish type.



Publications
Articles associated with genes and sequences of this homology group.

Gelsolin activity controls efficient early HIV-1 infection.
García-Expósito L, et al. Retrovirology 10, 39 (2013).
Multifunctional roles of gelsolin in health and diseases.
Li GH, et al. Med Res Rev 32, 999-1025 (2012).
Increased expression of serum gelsolin in patients with osteosarcoma.
Jin S, et al. Chin Med J (Engl) 125, 262-9 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ADF_gelsolin (cl15697)
  Actin depolymerization factor/cofilin- and gelsolin-like domains.
ADF_gelsolin (cl15697)
  Actin depolymerization factor/cofilin- and gelsolin-like domains.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gsn includes H.sapiens GSN and R.norvegicus Gsn.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (38 transcripts, 27 species)
Liliopsida - monocots (22 transcripts, 9 species)
Coniferopsida - conifers (2 transcripts, 2 species)

Chordata
Mammalia - mammals (24 transcripts, 17 species)
Actinopterygii - bony fishes (21 transcripts, 9 species)
Aves - birds (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

Write to the Help Desk