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HomoloGene:68520. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SLC2A1,  H.sapiens
solute carrier family 2 (facilitated glucose transporter), member 1
    NP_006507.2
492 aa
   SLC2A1,  P.troglodytes
solute carrier family 2 (facilitated glucose transporter), member 1
    XP_003308077.1
478 aa
   SLC2A1,  M.mulatta
solute carrier family 2 (facilitated glucose transporter), member 1
    XP_001090868.1
492 aa
   SLC2A1,  C.lupus
solute carrier family 2 (facilitated glucose transporter), member 1
    NP_001152798.1
492 aa
   SLC2A1,  B.taurus
solute carrier family 2 (facilitated glucose transporter), member 1
    NP_777027.1
492 aa
   Slc2a1,  M.musculus
solute carrier family 2 (facilitated glucose transporter), member 1
    NP_035530.2
492 aa
   Slc2a1,  R.norvegicus
solute carrier family 2 (facilitated glucose transporter), member 1
    NP_620182.1
492 aa
   SLC2A1,  G.gallus
solute carrier family 2 (facilitated glucose transporter), member 1
    NP_990540.1
490 aa
   slc2a1a,  D.rerio
solute carrier family 2 (facilitated glucose transporter), member 1a
    NP_001034897.1
488 aa
   slc2a1b,  D.rerio
solute carrier family 2 (facilitated glucose transporter), member 1b
    XP_002662574.1
489 aa
   AGOS_AFL034W,  E.gossypii
AGOS_AFL034W
    NP_985514.2
474 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Glucose transport defect, blood-brain barrier.



Publications
Articles associated with genes and sequences of this homology group.

The role of SLC2A1 in early onset and childhood absence epilepsies.
Muhle H, et al. Epilepsy Res 105, 229-33 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MFS (cd06174)
  The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
Sugar_tr (pfam00083)
  Sugar (and other) transporter.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc2a1 includes H.sapiens SLC2A1 and R.norvegicus Slc2a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (23 transcripts, 11 species)
Mammalia - mammals (18 transcripts, 14 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Oomycetes
Pythiales - oomycetes (2 transcripts, 1 species)
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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