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HomoloGene:9620. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CLDN1,  H.sapiens
claudin 1
    NP_066924.1
211 aa
   CLDN1,  P.troglodytes
claudin 1
    XP_516949.2
211 aa
   CLDN1,  M.mulatta
claudin 1
    XP_001093143.1
211 aa
   CLDN1,  C.lupus
claudin 1
    XP_850248.1
211 aa
   CLDN1,  B.taurus
claudin 1
    NP_001001854.1
211 aa
   Cldn1,  M.musculus
claudin 1
    NP_057883.1
211 aa
   Cldn1,  R.norvegicus
claudin 1
    NP_113887.2
211 aa
   CLDN1,  G.gallus
claudin 1
    NP_001013629.1
211 aa
   cldn1,  X.tropicalis
claudin 1
    NP_001015704.1
211 aa
   cldn1,  D.rerio
claudin 1
    NP_571845.1
210 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis.



Publications
Articles associated with genes and sequences of this homology group.

Claudin 1 expression characterizes human uterine cervical reserve cells.
Zinner B, et al. J Histochem Cytochem 61, 880-8 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PMP22_Claudin (cl15797)
  PMP-22/EMP/MP20/Claudin family.
PMP22_Claudin (pfam00822)
  PMP-22/EMP/MP20/Claudin family.
Claudin_2 (cl17758)
  PMP-22/EMP/MP20/Claudin tight junction.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cldn1 includes H.sapiens CLDN1 and R.norvegicus Cldn1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

 

 

 

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