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HomoloGene:8915. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MFN2,  H.sapiens
mitofusin 2
    NP_001121132.1
757 aa
   MFN2,  P.troglodytes
mitofusin 2
    XP_003307856.1
757 aa
   MFN2,  M.mulatta
mitofusin 2
    XP_002802232.1
634 aa
   MFN2,  C.lupus
mitofusin 2
    XP_005618048.1
762 aa
   MFN2,  B.taurus
mitofusin 2
    NP_001177198.1
757 aa
   Mfn2,  M.musculus
mitofusin 2
    NP_001272849.1
757 aa
   Mfn2,  R.norvegicus
mitofusin 2
    NP_570964.4
757 aa
   LOC100911485,  R.norvegicus
mitofusin-2-like
    XP_003750134.1
757 aa
   MFN2,  G.gallus
mitofusin 2
    XP_004947560.1
755 aa
   mfn2,  X.tropicalis
mitofusin 2
    NP_001016514.1
756 aa
   mfn2,  D.rerio
mitofusin 2
    NP_001121726.1
757 aa
   Marf,  D.melanogaster
Mitochondrial assembly regulatory factor
    NP_996357.1
810 aa
   AgaP_AGAP001802,  A.gambiae
AgaP_AGAP001802
    XP_321258.5
776 aa
   fzo-1,  C.elegans
fzo-1
    NP_495161.1
774 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hereditary motor and sensory neuropathy VI.
Charcot-Marie-Tooth disease, type 2A2.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Fzo_mitofusin (pfam04799)
  fzo-like conserved region.
YlqF_related_GTPase (cl17249)
  Circularly permuted YlqF-related GTPases.
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mfn2 includes H.sapiens MFN2 and R.norvegicus Mfn2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 12 species)
Actinopterygii - bony fishes (12 transcripts, 8 species)
Aves - birds (3 transcripts, 1 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 8 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

 

 

 

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