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HomoloGene:75060. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TLR7,  H.sapiens
toll-like receptor 7
    NP_057646.1
1049 aa
   TLR7,  P.troglodytes
toll-like receptor 7
    NP_001123605.1
1049 aa
   TLR7,  M.mulatta
toll-like receptor 7
    NP_001123898.1
1049 aa
   TLR7,  C.lupus
toll-like receptor 7
    NP_001041589.1
1050 aa
   TLR7,  B.taurus
toll-like receptor 7
    NP_001028933.1
1058 aa
   Tlr7,  M.musculus
toll-like receptor 7
    NP_573474.1
1050 aa
   Tlr7,  R.norvegicus
toll-like receptor 7
    NP_001091051.1
1050 aa
   TLR7,  G.gallus
toll-like receptor 7
    NP_001011688.1
1059 aa
   tlr7,  X.tropicalis
toll-like receptor 7
    NP_001120883.1
1054 aa
   tlr7,  D.rerio
toll-like receptor 7
    XP_003199309.1
1045 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Toll-like receptor 7 rapidly relaxes human airways.
Drake MG, et al. Am J Respir Crit Care Med 188, 664-72 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR_8 (pfam13855)
  Leucine rich repeat.
TIR_2 (cl15770)
  TIR domain.
LRRCT (smart00082)
  Leucine rich repeat C-terminal domain.
LRRNT (cl02423)
  Leucine rich repeat N-terminal domain.
TIR_2 (cl17458)
  TIR domain.
LRR_8 (pfam13855)
  Leucine rich repeat.
TIR_2 (cl17458)
  TIR domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tlr7 includes H.sapiens TLR7 and R.norvegicus Tlr7.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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