Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
HomoloGene:11556. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PRDM14,  H.sapiens
PR domain containing 14
    NP_078780.1
571 aa
   PRDM14,  P.troglodytes
PR domain containing 14
    XP_519800.2
571 aa
   PRDM14,  M.mulatta
PR domain containing 14
    XP_002805420.1
571 aa
   PRDM14,  C.lupus
PR domain containing 14
    XP_003640063.1
571 aa
   PRDM14,  B.taurus
PR domain containing 14
    NP_001178193.1
571 aa
   Prdm14,  M.musculus
PR domain containing 14
    NP_001074678.2
561 aa
   LOC100365184,  R.norvegicus
PR domain containing 14-like
    XP_003749932.1
559 aa
   LOC100858709,  G.gallus
PR domain zinc finger protein 14-like
    XP_003640888.1
480 aa
   prdm14,  X.tropicalis
PR domain containing 14
    XP_002937124.1
589 aa
   prdm14,  D.rerio
PR domain containing 14
    NP_001157303.1
517 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells.
Tsuneyoshi N, et al. Biochem Biophys Res Commun 367, 899-905 (2008).
Gene amplification and overexpression of PRDM14 in breast cancers.
Nishikawa N, et al. Cancer Res 67, 9649-57 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SET (pfam00856)
  SET domain.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
SET (cl02566)
  SET domain.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-C2H2 (pfam00096)
  Zinc finger, C2H2 type.
SET (cl02566)
  SET domain.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prdm14 includes H.sapiens PRDM14.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (4 transcripts, 4 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

Write to the Help Desk