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HomoloGene:1072. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   LPAR1,  H.sapiens
lysophosphatidic acid receptor 1
    NP_001392.2
364 aa
   LPAR1,  P.troglodytes
lysophosphatidic acid receptor 1
    XP_001147476.1
364 aa
   LPAR1,  M.mulatta
lysophosphatidic acid receptor 1
    XP_001106044.1
364 aa
   LPAR1,  C.lupus
lysophosphatidic acid receptor 1
    XP_532031.3
364 aa
   LPAR1,  B.taurus
lysophosphatidic acid receptor 1
    NP_776472.1
364 aa
   Lpar1,  M.musculus
lysophosphatidic acid receptor 1
    NP_766577.1
364 aa
   Lpar1,  R.norvegicus
lysophosphatidic acid receptor 1
    NP_446388.1
364 aa
   LPAR1,  G.gallus
lysophosphatidic acid receptor 1
    NP_001108554.1
369 aa
   lpar1,  X.tropicalis
lysophosphatidic acid receptor 1
    NP_001096313.1
366 aa
   lpar1,  D.rerio
lysophosphatidic acid receptor 1
    NP_001004502.2
346 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Necessity of lysophosphatidic acid receptor 1 for development of arthritis.
Miyabe Y, et al. Arthritis Rheum 65, 2037-47 (2013).
Bone defects in LPA receptor genetically modified mice.
Salles JP, et al. Biochim Biophys Acta 1831, 93-8 (2013).
Enhancement of endothelial cell migration by constitutively active LPA(1)-expressing tumor cells.
Kitayoshi M, et al. Biochem Biophys Res Commun 422, 339-43 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lpar1 includes H.sapiens LPAR1 and R.norvegicus Lpar1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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