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HomoloGene:55937. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SMAD3,  H.sapiens
SMAD family member 3
    NP_005893.1
425 aa
   SMAD3,  P.troglodytes
SMAD family member 3
    XP_001159972.2
425 aa
   SMAD3,  M.mulatta
SMAD family member 3
    XP_001111262.1
425 aa
   SMAD3,  C.lupus
SMAD family member 3
    NP_001164300.1
425 aa
   SMAD3,  B.taurus
SMAD family member 3
    NP_001192734.1
425 aa
   Smad3,  M.musculus
SMAD family member 3
    NP_058049.3
425 aa
   Smad3,  R.norvegicus
SMAD family member 3
    NP_037227.1
425 aa
   SMAD3,  G.gallus
SMAD family member 3
    NP_989806.1
426 aa
   smad3,  X.tropicalis
SMAD family member 3
    NP_001008436.1
425 aa
   smad3b,  D.rerio
MAD, mothers against decapentaplegic homolog 3b (Drosophila)
    NP_778258.1
423 aa
   Smox,  D.melanogaster
Smad on X
    NP_511079.1
486 aa
   AgaP_AGAP009777,  A.gambiae
AgaP_AGAP009777
    XP_318870.3
506 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Down-regulation of Smad3 accelerates palatal wound repair.
Yoneda N, et al. J Dent Res 92, 716-20 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MH1 (cl00055)
  N-terminal Mad Homology 1 (MH1) domain.
MH1 (cl00055)
  N-terminal Mad Homology 1 (MH1) domain.
MH2 (cl00056)
  C-terminal Mad Homology 2 (MH2) domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Smad3 includes H.sapiens SMAD3 and R.norvegicus Smad3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (13 transcripts, 6 species)
Mammalia - mammals (11 transcripts, 11 species)
Aves - birds (4 transcripts, 3 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 6 species)
Branchiopoda - crustaceans (3 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (6 transcripts, 2 species)
Turbellaria - flatworms (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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