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HomoloGene:481. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   IL1B,  H.sapiens
interleukin 1, beta
    NP_000567.1
269 aa
   IL1B,  P.troglodytes
interleukin 1, beta
    XP_001147075.1
269 aa
   IL1B,  M.mulatta
interleukin 1, beta
    NP_001036221.1
269 aa
   IL1B,  C.lupus
interleukin 1, beta
    NP_001033060.1
265 aa
   IL1B,  B.taurus
interleukin 1, beta
    NP_776518.1
266 aa
   Il1b,  M.musculus
interleukin 1 beta
    NP_032387.1
269 aa
   Il1b,  R.norvegicus
interleukin 1 beta
    NP_113700.2
268 aa
   il1b,  X.tropicalis
interleukin 1, beta
    XP_002932618.1
286 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Gastric cancer risk after H. pylori infection.



Publications
Articles associated with genes and sequences of this homology group.

IL1 cluster gene polymorphisms in Macedonian patients with chronic periodontitis.
Atanasovska-Stojanovska A, et al. Bratisl Lek Listy 114, 380-5 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IL1_propep (pfam02394)
  Interleukin-1 propeptide.
IL1 (cl00094)
  Interleukin-1 homologes; Cytokines with various biological functions. Interleukin 1 alpha and beta are also known as hematopoietin and catabolin. This family also contains interleukin-1 receptor antagonists (inhibitors).
IL1_propep (pfam02394)
  Interleukin-1 propeptide.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Il1b includes H.sapiens IL1B and R.norvegicus Il1b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Aves - birds (2 transcripts, 2 species)

 

 

 

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