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HomoloGene:1264. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ASIP,  H.sapiens
agouti signaling protein
    NP_001663.2
132 aa
   ASIP,  P.troglodytes
agouti signaling protein
    NP_001129099.1
132 aa
   LOC709156,  M.mulatta
agouti-signaling protein-like
    XP_001097667.1
58 aa
   ASIP,  C.lupus
agouti signaling protein
    NP_001007264.1
131 aa
   ASIP,  B.taurus
agouti signaling protein
    NP_996674.1
133 aa
   a,  M.musculus
nonagouti
    NP_056585.2
131 aa
   Asip,  R.norvegicus
agouti signaling protein
    NP_443211.1
131 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Skin/hair/eye pigmentation 9, dark/light hair.



Publications
Articles associated with genes and sequences of this homology group.

Maternal cholestasis during pregnancy programs metabolic disease in offspring.
Papacleovoulou G, et al. J Clin Invest 123, 3172-81 (2013).
Bisphenol a exposure disrupts genomic imprinting in the mouse.
Susiarjo M, et al. PLoS Genet 9, e1003401 (2013).
Variants at chromosome 20 (ASIP locus) and melanoma risk.
Maccioni L, et al. Int J Cancer 132, 42-54 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Agouti (cl04902)
  Agouti protein.
Agouti (cl04902)
  Agouti protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus a includes H.sapiens ASIP and R.norvegicus Asip.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 13 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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