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HomoloGene:73884. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   SLC11A1,  H.sapiens
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
    NP_000569.3
550 aa
   SLC11A1,  P.troglodytes
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
    XP_001156701.1
550 aa
   SLC11A1,  M.mulatta
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
    XP_001089328.1
517 aa
   SLC11A1,  C.lupus
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
    NP_001013873.1
547 aa
   SLC11A1,  B.taurus
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
    NP_777077.1
548 aa
   Slc11a1,  M.musculus
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
    NP_038640.2
548 aa
   Slc11a1,  R.norvegicus
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
    NP_001026828.1
507 aa
   SLC11A1,  G.gallus
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
    NP_990295.1
555 aa
   slc11a1,  X.tropicalis
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
    XP_002933999.2
547 aa
   NRAMP3,  A.thaliana
NRAMP3
    NP_179896.1
509 aa
   NRAMP2,  A.thaliana
NRAMP2
    NP_175157.1
530 aa
   NRAMP4,  A.thaliana
NRAMP4
    NP_201534.1
512 aa
   Os03g0208500,  O.sativa
Os03g0208500
    NP_001049330.1
524 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Mycobacterium tuberculosis, susceptibility to infection by.



Publications
Articles associated with genes and sequences of this homology group.

Multiple targeting motifs direct NRAMP1 into lysosomes.
Cheng X & Wang H. Biochem Biophys Res Commun 419, 578-83 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MntH (cl15845)
  Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc11a1 includes H.sapiens SLC11A1 and R.norvegicus Slc11a1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (9 transcripts, 8 species)
Eudicotyledons - eudicots (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

 

 

 

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