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HomoloGene:20695. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TLR2,  H.sapiens
toll-like receptor 2
    NP_003255.2
784 aa
   TLR2,  P.troglodytes
toll-like receptor 2
    NP_001123941.1
784 aa
   TLR2,  M.mulatta
toll-like receptor 2
    NP_001123897.1
784 aa
   TLR2,  C.lupus
toll-like receptor 2
    NP_001005264.2
785 aa
   TLR2,  B.taurus
toll-like receptor 2
    NP_776622.1
784 aa
   Tlr2,  M.musculus
toll-like receptor 2
    NP_036035.3
784 aa
   Tlr2,  R.norvegicus
toll-like receptor 2
    NP_942064.1
784 aa
   LOC100858824,  G.gallus
toll-like receptor 2 type-1-like
    XP_004940943.1
854 aa
   TLR2-2,  G.gallus
toll-like receptor 2
    NP_001155122.1
732 aa
   TLR2-1,  G.gallus
toll-like receptor 2 type1
    NP_989609.1
793 aa
   LOC100485771,  X.tropicalis
toll-like receptor 2 type-2-like
    XP_002933537.1
780 aa
   LOC100485927,  X.tropicalis
toll-like receptor 2 type-2-like
    XP_002933538.2
746 aa
   tlr2,  D.rerio
toll-like receptor 2
    NP_997977.1
788 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Colorectal cancer, susceptibility to.
Leprosy, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Immunolocalization of toll-like receptor 2 in viral warts and molluscum contagiosum.
Bakry OA, et al. Anal Quant Cytopathol Histpathol 35, 316-23 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR_8 (pfam13855)
  Leucine rich repeat.
LRRCT (smart00082)
  Leucine rich repeat C-terminal domain.
COG4886 (COG4886)
  Leucine-rich repeat (LRR) protein [Function unknown].
LRR_RI (cd00116)
  Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
LRR_4 (pfam12799)
  Leucine Rich repeats (2 copies).
LRR_8 (pfam13855)
  Leucine rich repeat.
TIR_2 (cl17458)
  TIR domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tlr2 includes H.sapiens TLR2 and R.norvegicus Tlr2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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