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HomoloGene:84829. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   DIAPH3,  H.sapiens
diaphanous-related formin 3
    NP_001245295.1
1182 aa
   DIAPH3,  P.troglodytes
diaphanous homolog 3 (Drosophila)
    XP_509808.3
1260 aa
   DIAPH3,  M.mulatta
diaphanous homolog 3 (Drosophila)
    XP_002800823.1
1150 aa
   DIAPH3,  C.lupus
diaphanous-related formin 3
    XP_005633999.1
1121 aa
   DIAPH3,  B.taurus
diaphanous-related formin 3
    NP_001179543.1
1181 aa
   Diap3,  M.musculus
diaphanous homolog 3 (Drosophila)
    NP_062644.1
1171 aa
   Diaph3,  R.norvegicus
diaphanous-related formin 3
    XP_002728345.2
1172 aa
   diaph3,  X.tropicalis
diaphanous-related formin 3
    XP_002936971.2
1125 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.

Filopodia formation induced by active mDia2/Drf3.
Block J, et al. J Microsc 231, 506-17 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FH2 (pfam02181)
  Formin Homology 2 Domain.
Drf_FH3 (pfam06367)
  Diaphanous FH3 Domain.
Drf_GBD (pfam06371)
  Diaphanous GTPase-binding Domain.
Drf_FH3 (pfam06367)
  Diaphanous FH3 Domain.
Drf_GBD (pfam06371)
  Diaphanous GTPase-binding Domain.
HrpJ (cl15454)
  HrpJ-like domain.
FH2 (cl19758)
  Formin Homology 2 Domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Diap3 includes H.sapiens DIAPH3 and R.norvegicus Diaph3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 11 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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