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HomoloGene:11003. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   TRPV4,  H.sapiens
transient receptor potential cation channel, subfamily V, member 4
    NP_067638.3
871 aa
   TRPV4,  P.troglodytes
transient receptor potential cation channel, subfamily V, member 4
    XP_003314024.1
806 aa
   TRPV4,  C.lupus
transient receptor potential cation channel, subfamily V, member 4
    NP_001120787.1
871 aa
   TRPV4,  B.taurus
transient receptor potential cation channel, subfamily V, member 4
    NP_001179314.1
871 aa
   Trpv4,  M.musculus
transient receptor potential cation channel, subfamily V, member 4
    NP_071300.2
871 aa
   Trpv4,  R.norvegicus
transient receptor potential cation channel, subfamily V, member 4
    NP_076460.1
871 aa
   TRPV4,  G.gallus
transient receptor potential cation channel, subfamily V, member 4
    NP_990023.1
852 aa
   trpv4,  X.tropicalis
transient receptor potential cation channel, subfamily V, member 4
    XP_002932129.1
868 aa
   trpv4,  D.rerio
transient receptor potential cation channel, subfamily V, member 4
    NP_001036195.1
841 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Brachyolmia type 3.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ion_trans (pfam00520)
  Ion transport protein.
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
Ion_trans (pfam00520)
  Ion transport protein.
Ank_2 (pfam12796)
  Ankyrin repeats (3 copies).
Ank_4 (pfam13637)
  Ankyrin repeats (many copies).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Trpv4 includes H.sapiens TRPV4 and R.norvegicus Trpv4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Amphibia - amphibians (4 transcripts, 2 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)

 

 

 

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