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HomoloGene:43236. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ANTXR2,  H.sapiens
anthrax toxin receptor 2
    NP_477520.2
488 aa
   ANTXR2,  P.troglodytes
anthrax toxin receptor 2
    XP_001145172.1
488 aa
   ANTXR2,  M.mulatta
anthrax toxin receptor 2
    XP_001090691.2
488 aa
   ANTXR2,  C.lupus
anthrax toxin receptor 2
    XP_544943.4
496 aa
   ANTXR2,  B.taurus
anthrax toxin receptor 2
    NP_001070294.1
488 aa
   Antxr2,  M.musculus
anthrax toxin receptor 2
    NP_598499.1
487 aa
   Antxr2,  R.norvegicus
anthrax toxin receptor 2
    XP_006250767.1
481 aa
   ANTXR2,  G.gallus
anthrax toxin receptor 2
    XP_420539.4
444 aa
   antxr2,  X.tropicalis
anthrax toxin receptor 2
    NP_001121460.1
488 aa
   antxr2a,  D.rerio
anthrax toxin receptor 2a
    NP_001038174.2
478 aa
   antxr2b,  D.rerio
anthrax toxin receptor 2b
    NP_001096038.1
487 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Fibromatosis, juvenile hyaline.
Hyalinosis, infantile systemic.



Publications
Articles associated with genes and sequences of this homology group.

Human genetic variation altering anthrax toxin sensitivity.
Martchenko M, et al. Proc Natl Acad Sci U S A 109, 2972-7 (2012).
Hyalinosis, Inherited Systemic
Shieh JTC, et al. (1993).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ant_C (pfam05586)
  Anthrax receptor C-terminus region.
Anth_Ig (pfam05587)
  Anthrax receptor extracellular domain.
vWFA (cl00057)
  Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Antxr2 includes H.sapiens ANTXR2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (13 transcripts, 9 species)
Mammalia - mammals (12 transcripts, 10 species)
Aves - birds (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 1 species)

 

 

 

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