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HomoloGene:1531. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FMR1,  H.sapiens
fragile X mental retardation 1
    NP_002015.1
632 aa
   FMR1,  P.troglodytes
fragile X mental retardation 1
    XP_521294.3
632 aa
   FMR1,  M.mulatta
fragile X mental retardation 1
    XP_001087617.2
718 aa
   FMR1,  C.lupus
fragile X mental retardation 1
    XP_866618.1
632 aa
   FMR1,  B.taurus
fragile X mental retardation 1
    NP_001179079.1
632 aa
   Fmr1,  M.musculus
fragile X mental retardation syndrome 1
    NP_032057.2
614 aa
   Fmr1,  R.norvegicus
fragile X mental retardation 1
    NP_434691.1
581 aa
   FMR1,  G.gallus
fragile X mental retardation 1
    XP_420363.1
565 aa
   fmr1,  X.tropicalis
fragile X mental retardation 1
    NP_001005454.1
590 aa
   fmr1,  D.rerio
fragile X mental retardation 1
    NP_694495.1
569 aa
   Fmr1,  D.melanogaster
Fmr1
    NP_731444.1
681 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Fragile X tremor/ataxia syndrome.
Fragile X syndrome.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Agenet (smart00743)
  Tudor-like domain present in plant sequences.
KH_1 (pfam00013)
  KH domain.
Agenet (pfam05641)
  Agenet domain.
FXR1P_C (pfam12235)
  Fragile X-related 1 protein C terminal.
Agenet (pfam05641)
  Agenet domain.
FXR1P_C (pfam12235)
  Fragile X-related 1 protein C terminal.
RAM (pfam15320)
  mRNA cap methylation, RNMT-activating mini protein.
KH-I (cl17245)
  K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fmr1 includes H.sapiens FMR1 and R.norvegicus Fmr1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (12 transcripts, 7 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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