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HomoloGene:7920. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   RLIM,  H.sapiens
ring finger protein, LIM domain interacting
    NP_057204.2
624 aa
   RLIM,  P.troglodytes
ring finger protein, LIM domain interacting
    XP_001142065.1
620 aa
   RLIM,  M.mulatta
ring finger protein, LIM domain interacting
    XP_001096367.1
624 aa
   RLIM,  C.lupus
ring finger protein, LIM domain interacting
    XP_005641563.1
625 aa
   Rlim,  M.musculus
ring finger protein, LIM domain interacting
    NP_035406.3
600 aa
   Rlim,  R.norvegicus
ring finger protein, LIM domain interacting
    NP_001020063.1
603 aa
   LOC100910646,  R.norvegicus
E3 ubiquitin-protein ligase RLIM-like
    XP_006257203.1
603 aa
   RLIM,  G.gallus
ring finger protein, LIM domain interacting
    NP_990159.1
593 aa
   rlim,  X.tropicalis
ring finger protein, LIM domain interacting
    NP_001016091.1
639 aa
   LOC562487,  D.rerio
E3 ubiquitin-protein ligase RNF12-A-like
    XP_686027.4
638 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

RLIM interacts with Smurf2 and promotes TGF-β induced U2OS cell migration.
Huang Y, et al. Biochem Biophys Res Commun 414, 181-5 (2011).
RNF12 activates Xist and is essential for X chromosome inactivation.
Barakat TS, et al. PLoS Genet 7, e1002001 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RING (cl17238)
  RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rlim includes H.sapiens RLIM and R.norvegicus Rnf12.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (5 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)

 

 

 

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