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HomoloGene:7920. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   RLIM,  H.sapiens
ring finger protein, LIM domain interacting
624 aa
   RLIM,  P.troglodytes
ring finger protein, LIM domain interacting
620 aa
   RLIM,  M.mulatta
ring finger protein, LIM domain interacting
624 aa
   RLIM,  C.lupus
ring finger protein, LIM domain interacting
625 aa
   Rlim,  M.musculus
ring finger protein, LIM domain interacting
600 aa
   Rlim,  R.norvegicus
ring finger protein, LIM domain interacting
603 aa
   LOC100910646,  R.norvegicus
E3 ubiquitin-protein ligase RLIM-like
603 aa
   RLIM,  G.gallus
ring finger protein, LIM domain interacting
593 aa
   rlim,  X.tropicalis
ring finger protein, LIM domain interacting
639 aa
   LOC562487,  D.rerio
E3 ubiquitin-protein ligase RNF12-A-like
638 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

RLIM interacts with Smurf2 and promotes TGF-β induced U2OS cell migration.
Huang Y, et al. Biochem Biophys Res Commun 414, 181-5 (2011).
RNF12 activates Xist and is essential for X chromosome inactivation.
Barakat TS, et al. PLoS Genet 7, e1002001 (2011).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RING (cl17238)
  RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rlim includes H.sapiens RLIM and R.norvegicus Rnf12.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (5 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)




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