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HomoloGene:74303. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   PDGFB,  H.sapiens
platelet-derived growth factor beta polypeptide
    NP_002599.1
241 aa
   PDGFB,  P.troglodytes
platelet-derived growth factor beta polypeptide
    XP_515140.2
241 aa
   PDGFB,  M.mulatta
platelet-derived growth factor beta polypeptide
    XP_001097395.1
241 aa
   PDGFB,  C.lupus
platelet-derived growth factor beta polypeptide
    NP_001003383.1
242 aa
   PDGFB,  B.taurus
platelet-derived growth factor beta polypeptide
    NP_001017953.2
241 aa
   Pdgfb,  M.musculus
platelet derived growth factor, B polypeptide
    NP_035187.2
241 aa
   Pdgfb,  R.norvegicus
platelet-derived growth factor beta polypeptide
    NP_113712.1
241 aa
   PDGFB,  G.gallus
platelet-derived growth factor beta polypeptide
    NP_989601.2
251 aa
   pdgfb,  X.tropicalis
platelet-derived growth factor beta polypeptide
    XP_002933796.1
240 aa
   LOC796490,  D.rerio
uncharacterized LOC796490
    XP_005171670.1
483 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Dermatofibrosarcoma protuberans.
Giant-cell fibroblastoma.
Meningioma, SIS-related.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PDGF_N (pfam04692)
  Platelet-derived growth factor, N terminal region.
PDGF_N (pfam04692)
  Platelet-derived growth factor, N terminal region.
PDGF (cl00116)
  Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pdgfb includes H.sapiens PDGFB and R.norvegicus Pdgfb.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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