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HomoloGene:393. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   STK11,  H.sapiens
serine/threonine kinase 11
    NP_000446.1
433 aa
   STK11,  P.troglodytes
serine/threonine kinase 11
    XP_524028.2
433 aa
   STK11,  M.mulatta
serine/threonine kinase 11
    XP_001093806.1
433 aa
   STK11,  C.lupus
serine/threonine kinase 11
    XP_542206.2
439 aa
   Stk11,  M.musculus
serine/threonine kinase 11
    NP_035622.1
436 aa
   Stk11,  R.norvegicus
serine/threonine kinase 11
    NP_001101539.1
436 aa
   STK11,  G.gallus
serine/threonine kinase 11
    NP_001039298.1
440 aa
   stk11,  X.tropicalis
serine/threonine kinase 11
    NP_001016533.1
432 aa
   stk11,  D.rerio
serine/threonine kinase 11
    NP_001017839.1
440 aa
   AgaP_AGAP003158,  A.gambiae
AgaP_AGAP003158
    XP_312848.5
566 aa
   par-4,  C.elegans
par-4
    NP_001256779.1
613 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Peutz-Jeghers syndrome.
Testicular tumor, sporadic.
Melanoma, malignant sporadic.
Pancreatic cancer, sporadic.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Stk11 includes H.sapiens STK11 and R.norvegicus Stk11.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 10 species)
Actinopterygii - bony fishes (12 transcripts, 7 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 9 species)
Arachnida - arachnids (2 transcripts, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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