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HomoloGene:7318. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   FOXM1,  H.sapiens
forkhead box M1
    NP_973731.1
801 aa
   FOXM1,  P.troglodytes
forkhead box M1
    XP_001154937.1
748 aa
   FOXM1,  M.mulatta
forkhead box M1
    XP_002798495.1
727 aa
   FOXM1,  C.lupus
forkhead box M1
    XP_543870.2
765 aa
   FOXM1,  B.taurus
forkhead box M1
    XP_005207333.1
760 aa
   Foxm1,  M.musculus
forkhead box M1
    NP_032047.4
757 aa
   Foxm1,  R.norvegicus
forkhead box M1
    NP_113821.2
771 aa
   FOXM1,  G.gallus
forkhead box M1
    NP_001012973.1
795 aa
   foxm1,  X.tropicalis
forkhead box M1
    XP_002941428.1
754 aa
   foxm1,  D.rerio
forkhead box M1
    NP_957391.1
623 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Signaling of miRNAs-FOXM1 in cancer and potential targeted therapy.
Shi M, et al. Curr Drug Targets 14, 1192-202 (2013).
MEK inhibition increases lapatinib sensitivity via modulation of FOXM1.
Gayle SS, et al. Curr Med Chem 20, 2486-99 (2013).
FOX(M1) news--it is cancer.
Halasi M & Gartel AL. Mol Cancer Ther 12, 245-54 (2013).
FOXM1 is an oncogenic mediator in Ewing Sarcoma.
Christensen L, et al. PLoS One 8, e54556 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FH (cl00061)
  Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Foxm1 includes H.sapiens FOXM1 and R.norvegicus Foxm1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Aves - birds (3 transcripts, 1 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

 

 

 

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