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HomoloGene:413. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   APRT,  H.sapiens
adenine phosphoribosyltransferase
    NP_000476.1
180 aa
   APRT,  P.troglodytes
adenine phosphoribosyltransferase
    XP_003952966.1
180 aa
   APRT,  M.mulatta
adenine phosphoribosyltransferase
    XP_001089867.1
180 aa
   APRT,  C.lupus
adenine phosphoribosyltransferase
    XP_536752.2
180 aa
   APRT,  B.taurus
adenine phosphoribosyltransferase
    NP_001020505.1
180 aa
   Aprt,  M.musculus
adenine phosphoribosyl transferase
    NP_033828.2
180 aa
   Aprt,  R.norvegicus
adenine phosphoribosyl transferase
    NP_001013079.1
180 aa
   APRT,  G.gallus
adenine phosphoribosyltransferase
    NP_001264576.1
179 aa
   aprt,  X.tropicalis
adenine phosphoribosyltransferase
    NP_001007941.1
180 aa
   aprt,  D.rerio
adenine phosphoribosyl transferase
    NP_956962.1
177 aa
   Aprt,  D.melanogaster
Adenine phosphoribosyltransferase
    NP_476637.1
182 aa
   AgaP_AGAP005723,  A.gambiae
AgaP_AGAP005723
    XP_315739.4
187 aa
   T19B4.3,  C.elegans
T19B4.3
    NP_491663.1
185 aa
   APT1,  S.cerevisiae
APT1
    NP_013690.1
187 aa
   KLLA0B01309g,  K.lactis
KLLA0B01309g
    XP_451589.1
187 aa
   AGOS_AER325W,  E.gossypii
AGOS_AER325W
    NP_985181.1
187 aa
   apt1,  S.pombe
apt1
    NP_594433.1
188 aa
   MGG_17399,  M.oryzae
MGG_17399
    XP_003718359.1
216 aa
   NCU02090,  N.crassa
NCU02090
    XP_963727.2
171 aa
   APT1,  A.thaliana
APT1
    NP_564284.1
243 aa
   Os12g0589100,  O.sativa
Os12g0589100
    NP_001067164.1
240 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

D.melanogaster
Mutant flies are resistant to the toxic effects of dietary purine.

H.sapiens
Urolithiasis, 2,8-dihydroxyadenine.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PRTases_typeI (cl00309)
  Phosphoribosyl transferase (PRT)-type I domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Aprt includes H.sapiens APRT and R.norvegicus Aprt.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 13 species)
Actinopterygii - bony fishes (9 transcripts, 9 species)
Aves - birds (4 transcripts, 2 species)
Amphibia - amphibians (4 transcripts, 2 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (11 transcripts, 10 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (4 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (43 transcripts, 32 species)
Liliopsida - monocots (12 transcripts, 9 species)
Coniferopsida - conifers (5 transcripts, 3 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (4 transcripts, 3 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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