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HomoloGene:56521. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   ABCC9,  H.sapiens
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    NP_005682.2
1549 aa
   ABCC9,  P.troglodytes
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    XP_001149414.1
1549 aa
   ABCC9,  M.mulatta
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    XP_001098888.1
1549 aa
   ABCC9,  C.lupus
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    XP_852746.1
1549 aa
   ABCC9,  B.taurus
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    XP_005207020.1
1549 aa
   Abcc9,  M.musculus
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    NP_035641.1
1546 aa
   Abcc9,  R.norvegicus
ATP-binding cassette, subfamily C (CFTR/MRP), member 9
    NP_037172.2
1545 aa
   ABCC9,  G.gallus
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    XP_004938045.1
1587 aa
   abcc9,  X.tropicalis
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    XP_004920363.1
824 aa
   abcc9,  D.rerio
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
    NP_001025325.1
1558 aa
   Sur,  D.melanogaster
Sulfonylurea receptor
    NP_477472.2
2171 aa
   AgaP_AGAP009799,  A.gambiae
AgaP_AGAP009799
    XP_553659.3
2025 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cardiomyopathy, dilated, 1O.



Publications
Articles associated with genes and sequences of this homology group.

Dominant missense mutations in ABCC9 cause CantĂș syndrome.
Harakalova M, et al. Nat Genet 44, 793-6 (2012).
CantĂș syndrome is caused by mutations in ABCC9.
van Bon BW, et al. Am J Hum Genet 90, 1094-101 (2012).
Vasodilation induced by oxygen/glucose deprivation is attenuated in cerebral arteries of SUR2 null mice.
Adebiyi A, et al. Am J Physiol Heart Circ Physiol 301, H1360-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ABC_membrane (pfam00664)
  ABC transporter transmembrane region.
ABC_membrane_2 (cl00549)
  ABC transporter transmembrane region 2.
ABC_ATPase (cl17201)
  ATP-binding cassette transporter nucleotide-binding domain.
ABC_membrane (pfam00664)
  ABC transporter transmembrane region.
ABC_ATPase (cl17201)
  ATP-binding cassette transporter nucleotide-binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Abcc9 includes H.sapiens ABCC9 and R.norvegicus Abcc9.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 8 species)
Actinopterygii - bony fishes (8 transcripts, 3 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

 

 

 

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