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HomoloGene:3576. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   GDF15,  H.sapiens
growth differentiation factor 15
    NP_004855.2
308 aa
   GDF15,  P.troglodytes
growth differentiation factor 15
    XP_003953462.1
308 aa
   GDF15,  M.mulatta
growth differentiation factor 15
    XP_001114375.1
308 aa
   GDF15,  C.lupus
growth differentiation factor 15
    XP_541938.1
307 aa
   GDF15,  B.taurus
growth differentiation factor 15
    NP_001193227.1
308 aa
   Gdf15,  M.musculus
growth differentiation factor 15
    NP_035949.2
303 aa
   Gdf15,  R.norvegicus
growth differentiation factor 15
    NP_062089.1
303 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Regulation and effects of GDF-15 in the retina following optic nerve crush.
Charalambous P, et al. Cell Tissue Res 353, 1-8 (2013).
GDF-15 prevents platelet integrin activation and thrombus formation.
Rossaint J, et al. J Thromb Haemost 11, 335-44 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TGF_beta (cl02510)
  Transforming growth factor beta like domain.
TGF_beta (cl02510)
  Transforming growth factor beta like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gdf15 includes H.sapiens GDF15 and R.norvegicus Gdf15.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)

 

 

 

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