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HomoloGene:4061. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   LAMP1,  H.sapiens
lysosomal-associated membrane protein 1
417 aa
   LAMP1,  P.troglodytes
lysosomal-associated membrane protein 1
417 aa
   LAMP1,  M.mulatta
lysosomal-associated membrane protein 1
416 aa
   LAMP1,  C.lupus
lysosomal-associated membrane protein 1
413 aa
   LAMP1,  B.taurus
lysosomal-associated membrane protein 1
409 aa
   Lamp1,  M.musculus
lysosomal-associated membrane protein 1
406 aa
   Lamp1,  R.norvegicus
lysosomal-associated membrane protein 1
407 aa
   LAMP1,  G.gallus
lysosomal-associated membrane protein 1
414 aa
   LOC563328,  D.rerio
lysosome-associated membrane glycoprotein 1-like
253 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Expression of the lysosomal-associated membrane protein-1 (LAMP-1) in astrocytomas.
Jensen SS, et al. Int J Clin Exp Pathol 6, 1294-305 (2013).
Pathogenic lysosomal depletion in Parkinson's disease.
Dehay B, et al. J Neurosci 30, 12535-44 (2010).
Relationship between CD107a expression and cytotoxic activity.
Aktas E, et al. Cell Immunol 254, 149-54 (2009).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TM_EGFR-like (cl17045)
  Transmembrane domain of the Epidermal Growth Factor Receptor family of Protein Tyrosine Kinases.
Lamp (pfam01299)
  Lysosome-associated membrane glycoprotein (Lamp).
Lamp (pfam01299)
  Lysosome-associated membrane glycoprotein (Lamp).

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lamp1 includes H.sapiens LAMP1 and R.norvegicus Lamp1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (15 transcripts, 12 species)
Actinopterygii - bony fishes (6 transcripts, 5 species)
Aves - birds (3 transcripts, 3 species)
Amniota - vertebrates (1 transcript, 1 species)




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